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Your Health: Treating Inflammatory Bowel Disease to Prevent Heart Disease

Over 650,000 people in the United States die of heart disease. That’s one in four deaths.

Now researchers are looking to the gut and an FDA-approved drug to treat inflammatory bowel disease to help prevent heart disease.

Lots of junk food and lots of sugar are staples in the standard American diet.

In fact, 63% of the calories consumed by Americans come from refined and processed foods, while 25% come from animal foods and only 12% come from plant foods.

“This diet changes the way the microbes that live in your gut work. They take components of that diet and then produce products that induce inflammation in your heart, in your arteries, and cause cardiovascular disease,” said Marianna Byndloss, DVM, PHD, assistant professor of pathology, microbiology, and immunology at the Vanderbilt University. Medical Center.

That’s why researchers at Vanderbilt University Medical Center are studying a drug used to treat inflammatory bowel disease to fix microbes or bacteria in the gut.

“A drug called five-amino salicylic acid, or 5-ASA, which is a drug that restores gut health and stops microbes from producing these bad metabolites,” Dr. Byndloss said.

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In animal studies, the drug increased levels of good bacteria and decreased bad bacteria in the gut.